Curiosity, Logic and Personal Relevance

Courtesy of Yaron Koler — gifted software engineer, friend and liver cancer survivor

If you are like me, you are intellectually curious and eager to improve in your personal, family and work dimensions. There is a lot of useful information online, from choosing mattresses to strengthening your upper back to learning Arabic. A lot of junk and darkness too which you need to ignore.

The thought-process of developing an idea to product-market fit

As a tech entrepreneur, I am curious about the process of taking an idea from gestation to implementation to wide-spread acceptance. A nephew, who is a very very smart boy and in his third year of chemical engineering recently asked me how how he…

When defense in depth fails — two deadly sins

Protecting complex systems requires quantitative threat modeling

Defense in depth is a security mantra, usually for very good military security and information security reasons. However — defense in depth may be a very bad idea, if your fundamental assumptions are wrong or you get blinded by security technology.

The sin of wrong assumptions

In the defense space — we can learn from military history that incorrect security assumptions carry a high price tag.

The 1973 Yom Kippur war that resulted in a stunning Israel victory but cost 2,800 Israeli lives, and the recent American war in Iraq, that…

Think like an attacker and save the emotion for later.

Pretty soon those desks will be empty

To be able to do something before it exists,
sense before it becomes active,
and see before it sprouts.

The Book of Balance and Harmony (Chung-ho chi).
A medieval Taoist book

In early December 2017, the Israeli pharmaceutical generics company Teva announced it would lay off about 1,700 of its employees in Israel, who make up about 25% of all the company’s employees in Israel, out of a total workforce of 6,680 employees. …

Don’t look at drug studies. Look at your own product and patients first.

Crossing the chasm from R&D to patients is tricky


Better designs, site-less trials, all-digital data collection and PCM (patient compliance monitoring) can all save time and money in connected medical device clinical trials. This article will help you choose which strategies will be a good fit to help you validate your connected medical device and its intended use for submission to FDA.

What is the baseline cost? (hint don’t look at the costs of drug studies)

If you want to save, you need to know the price tag. Note that the costs of drug trials, including CRO and regulatory affairs is an order of magnitude higher than for connected medical…

Tel Aviv, not far from Bograshov.

The roles of trust, security and privacy in healthcare. If President Biden had told his psychiatrist he was gay, you can bet that it would be on Instagram and Facebook in 5′. So much for privacy.


The state or condition of being free from being observed or disturbed by other people.

The state of being free from public attention.

When it comes to healthcare information, there have always been two circles of trust — the trust relationship with your physician and the trust that you place in your healthcare provider/insurance company/government health service.

With social networks like Facebook, a third…

Your mental health in a tech startup.

Woman on phone. No mask.

Post-COVID-19, it’s a time when we are all remote-workers.

Startups looking for new ways to add value to customers. Large pharmas looking for ways to innovate without breaking the system.

It’s harder to compete but a lot easier to innovate today

To quote Bill Gates from 25 years ago. Gates was asked how Microsoft can compete in enterprise software when they only had business-unit capabilities.

Gates was quoted as saying that large enterprises are a collection of many business units, so he was not worried.

The same is true today — whether you are a business unit in Pfizer or a 5-person healthtech startup

Here are 7 tips for innovation in healthcare

Photo from Yaron Koler — a software engineer and liver cancer survivor

Back in 2011, I thought it would only be a question of time before we have a drive by execution of a politician with an ICD (implanted cardiac device).

There was a flurry of excitement about this sort of remote-control exploit that sort of died out although the vulnerabilities continue to surface.

There was even an episode of CSI New York that used the concept of an EMP to kill a person with an ICD.

In fact, a radio exploit of an ICD or embedded insulin pump might be almost impossible to identify unless the device itself was logging external…

Courtesy of Yaron Koler — a liver cancer survivor and software engineer

4 reasons why electronic health record systems need to go

Reason #1 — Electronic health record systems in the US are a burden instead of a productivity tool for physicians.

When you have a non-value added activity or an activity with negative ROI, the first thing to do is to eliminate it. A policy started by the Obama administration of stimulating adoption of electronic health records created a Golem who destroyed his creator.

For every 8 hours of scheduled patient time, ambulatory physicians spend more than 5 hours on the EHR... …

Why drug companies miss their data and safety targets

Sikorsky CH-53 Sea Stallions over Modiin — Israel Independence Day 2021 — Photo courtesy of Yaron Koler.

It’s been a long time since I posted; but this is one I’ve been wanting to share for a while. I have a sign over my desk in the office :

Never mistake activity for achievement — John Wooden

John Wooden was the legendary UCLA basketball coach who won NCAA national championships in a 12-year period as head coach for the UCLA Bruins, including a record seven in a row. Wooden coached players at UCLA who would later become stars — players like layers Kareem Abdul-Jabbar and Bill Walton. …

and you need to stop guessing.

Crowd sourcing AI with large global diverse groups of AI engineers

I honestly don’t know where or how to start this post.

I have more questions than answers.

It all started almost a year ago with an idea to create an API service that takes data from clinical trials and automate anomaly detection.

The what (“Anomaly detection of structured high-dimensional time-series data”) was clear. Build an online service to detect anomalies in clinical data; send a JSON structure and we’ll tell you what data samples are suspicious.

The why and who was also clear — help democratize clinical data anomaly detection and make devices and…

Danny Lieberman

I am a physicist by training, serious amateur musician and everyday biker. Working in cybersecurity and AI-driven monitoring of clinical trials.

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